Abstract

HERNANDEZ HERNANDEZ, Aymeé. Electrophysiological evolution of a group of patients with primary and secondary CIPD. Rev Cubana Invest Bioméd [online]. 2008, vol.27, n.1. ISSN 0864-0300.

Introduction: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) has different forms of presentation; the idiopathic form and that related to concurrent diseases. The neurophysiological studies play a fundamental role in the diagnosis. Objetives: We proposed to compare the electrophysiological evolution by analyzing the variables evaluated through the nervous conduction study of a group of patients with primary and secondary CIDP at two evolutive moments of the disease. Methods: 9 patients with primary CIDP and 6 with CIDP related to diabetes mellitus, multiple sclerosis and adenocarcinoma were studied. A nervous conduction study of the nerves of the extremities was performed at the moment of the diagnosis of the disease and a year after treatment. The electrophysiological variables were compared in both moments by using nonparametric statistical techniques. Results: The patients with primary CIDP showed evolutive improvement of the electrophysiological variables with normalization of the study in two cases. Patients with secondary CIDP got worse. Conclusions: It was concluded that patients with secondary CIDP showed a torpid electrophysiological evolution with reserved prognosis.

Keywords : Primary CIDP; secondary CIDP; neurophysiological studies; nervous conduction study; electrophysiological evolution; chronic inflammatory polyradiculopathy.

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