Abstract

GRONING ROQUE, Ernesto; GARCIA FERNANDEZ, Raymid; GARCIA BARRETO, David  and  HERNANDEZ CANERO, Alberto. Ambulatory control of arterial systolic pressure in hypertensive patients presenting with associated ischemic heart disease. Rev Cubana Invest Bioméd [online]. 2010, vol.29, n.3, pp.309-319. ISSN 0864-0300.

When ischemic heart disease is associated with arterial hypertension, treatment becomes a complex task. A group of 126 non-controlled patients with isolated systolic hypertension aged over 50 with associated ischemic heart disease was studied to assess the effect of an antihypertensive treatment strategy based on the combination of a b-blocker (Atenolol), a diuretic, and an angiotensin-converting enzyme inhibitor (ACEI) on the ambulatory control of arterial pressure. All patients were assessed at onset and 6, 24 and 52 weeks later. The percentage of patients achieving blood pressure control was 52.38 %; 54.76 % and 71.42 % at 6, 24 and 52 weeks respectively. The results showed that treatment was effective to control the arterial pressure and to reduce the angina episodes in the systolic hypertensive ones. To achieve it, most of patients needed two or three drugs indicating that this group of hypertensive and systolic patients in the main of third age and with an associated chronic stable ischemic heart disease needs an appropriate therapy with a frequent follow-up.

Keywords : Hypertension; ischemic hear disease; b-blocker.

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