SciELO - Scientific Electronic Library Online

vol.34 issue4Archetypes, terminologies and semantic interoperability in health author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




  • Have no cited articlesCited by SciELO

Related links

  • Have no similar articlesSimilars in SciELO


Revista Cubana de Investigaciones Biomédicas

Print version ISSN 0864-0300On-line version ISSN 1561-3011


CORONA LISBOA, José Luis. Genetic causes related to anomalies in sex differentiation in mammals. Rev Cubana Invest Bioméd [online]. 2015, vol.34, n.4, pp.378-383. ISSN 0864-0300.

Determination of genetic sex takes place at the time of fecundation whereas differentiation of gonadal and genital sexes occurs during critical periods of embrionary life. The factors that modify the mechanisms of sex differentiation are varied and their anatomical and pathological, genetic and molecular study have attracted many researchers interested in this topic. The objective of the present article was to describe the genetic anomalies related to the development in sexual morphophysiology of mammals, starting from a deductive approach on the basis of reported research works on this topic. According to the information, it was concluded that anomalies of the chromosomal, gonadal and genital sex respond to a series of genetic alterations that involve a set of enzymatic cascades affecting the normal course of the sexual morphophysiological development of the animal.

Keywords : anomaly; hermaphroditism; intersex; gonads; genitalia.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )


Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License