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Revista Cubana de Investigaciones Biomédicas

Print version ISSN 0864-0300On-line version ISSN 1561-3011


GUERRA BRETANA, Rosa Mayelín; DE ALMEIDA, Marcelo Sanmartin  and  DE SENA, Lídia Ágata. Bone adhesives based on cyanoacrylates. Rev Cubana Invest Bioméd [online]. 2017, vol.36, n.1, pp.1-9. ISSN 0864-0300.

Fast curing biocompatible adhesives are a promising alternative to the metallic devices used for immobilization of fractures of small bone fragments as well as for some maxillofacial surgical procedures. They may serve as supports during the curing process, and present some advantages with respect to conventional fixation methods by plates and screws, such as their ease of application and the biodegradability of the material. The objective of the present study is to analyze the literature about bone adhesives based on cyanoacrylates, presenting the characteristics of these biomaterials, as well as their advantages and disadvantages for the fixation of small bone fragments in maxillofacial surgery and orthopedics. Study of the bioactivity, degradability, in vitro cytotoxicity, in vivo implantation and adhesiveness of the materials evaluated reveal their biocompatibility and their capacity to bind bone tissue.

Keywords : bone adhesives; cyanoacrylates; biocompatibility.

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