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Revista Cubana de Investigaciones Biomédicas
On-line version ISSN 1561-3011
Abstract
ESPINOZA-CHIONG, César et al. Factors associated with tuberculosis and human immunodeficiency virus coinfection in a Peruvian hospital. Rev Cubana Invest Bioméd [online]. 2021, vol.40, n.3 Epub Sep 01, 2021. ISSN 1561-3011.
Introduction:
HIV infection and tuberculosis are two of the main epidemics that affect many Latin American countries, which have a two-way impact on each other, making them highly relevant diseases in public health.
Objective:
To identify the factors associated with tuberculosis and HIV coinfection in patients registered in the Tuberculosis Control Program of the Dos de Mayo National Hospital.
Methods:
A cross-sectional and analytical study was carried out. The medical records of hospitalized patients admitted to the Tuberculosis Control Program were reviewed. Those with a confirmatory test for Western Blot with active tuberculosis were considered coinfection with tuberculosis and HIV simultaneously. With the generalized linear models, p-values and prevalence ratios adjusted with a 95% CI were obtained.
Results:
Of the 289 patients, 30.1% had tuberculosis and HIV coinfection and was associated with being male (RPa: 2.11; 95% CI: 1.21-3.66), drug user (RPa: 1.71; 95% CI: 1.13-2.52) and have a history of previous tuberculosis infection (RPa: 2.35; 95% CI: 1.53-3.63). Likewise, it was inversely associated with age (RPa: 0.98; 95% CI: 0.97-0.99).
Conclusions:
According to the data, the prevalence of tuberculosis and HIV coinfection is high and there is a higher frequency of tuberculosis and HIV coinfection among men, at a younger age, those with a history of tuberculosis and those who consume drugs. It is important to implement actions to improve the diagnosis and treatment of both infectious diseases.
Keywords : tuberculosis; coinfection; HIV; seroprevalence.