Abstract

TENORIO BORROTO, Esvieta; AGUILA JIMENEZ, Edisleidys  and  MOLLINEDA DIOGO, Niurka. Evaluation of RLV deodorant toxicity in eyes. Rev Cubana Oftalmol [online]. 2001, vol.14, n.2. ISSN 0864-2176.

An evaluation of the possible irritant effect of a formulation (RLV) that will be used as a deodorant and whose active principle is hexamine, which is utilized as a urinary antiseptic, was made. This formulation was applied by ophthalmic route to 6 New Zealand breed rabbits during 7 days. The assessments take into consideration the macroscopic observations of the possible adverse effects that occur in the ocular structures. This evaluation is based on the method proposed by Draize, as well as on the guidelines of the OECD. According to the results obtained, the pharmaceutical form prepared at a concentration of 3 % for the deodorant does not cause irritation of the ocular structures.

Keywords : DEODORANTS [adverse effects]; DEODORANTS [toxicity]; IRRITANTS; RABBITS; ANIMALS, LABORATORY.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )