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Revista Cubana de Oftalmología

Print version ISSN 0864-2176On-line version ISSN 1561-3070


GUTIERREZ MAYDATA, Alfredo; LAVANDERO ESPINA, Aleida; RAMOS ARGILAGOS, Miguel E.  and  MARTINEZ NUNEZ, Eligio. Oxidative stress, feeding and antioxidant supplementation in ocular pathology: brief history and future vision. Rev Cubana Oftalmol [online]. 2007, vol.20, n.2. ISSN 0864-2176.

The eyes are at risk of suffering oxidative damage due to their high exposure to oxygen, a great deal of fatty acids in the retina and also to light, environmental pollutants and ultraviolet rays. The present paper discussed the evidence found about the possible role of oxidative damage in the pathogenesis of several eye diseases (glaucoma, cataract, diabetic retinopathy, macular degeneration) and the role of diet and antioxidant supplements in the prevention  and treatment of such diseases. At present, the current recommendations cover the importance of a varied diet with high contents of fruits and vegetables, non-smoking, avoiding excessive exposure to the sun and ultraviolet radiations and a stict control of glycemic levels in diabetic patients as the most effective antioxidant strategy. The proven benefits of antioxidant supplements are being researched at present.

Keywords : Oxidative stress; cataract; diabetic retinopathy; macular degeneration; senile; antioxidants.

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