Abstract

MESA HERNANDEZ, Eddy et al. Clinical and serological characterization of active ocular toxoplasmosis. Rev Cubana Oftalmol [online]. 2012, vol.25, n.1, pp.21-31. ISSN 0864-2176.

Objective: To report the clinical and serological features of active ocular toxoplasmosis in a group of patients. Methods: A cross-sectional observational and descriptive study was conducted in 54 eyes from an equal number of patients, with a diagnosis of active ocular toxoplasmosis. A complete ophthalmologic exam was performed; and indirect immunofluorescence was applied to estimate the anti-toxoplasma IgG antibodies levels in peripheral serum. Results: Male patients and 16-45 y age group prevailed. All of the patients presented with retinochoroiditis along with vitreous haze of variable density. Recurrent lesions prevailed in 51.9% of cases. Mild visual impairment was more common (46.3%,), being the retinal zone I the most compromised(53.7 %). Ig G was positive in 88.9% of patients; 1/32 dilution prevailed (38.9 %). The most frequent ocular complications were epiretinal membrane (7. 41 %), vitreous opacities (5.56 %) and secondary glaucoma (5.56 %). Conclusion: In this study, the epidemiological characteristics of patients were similar to those described in literature. The level of visual impairment was related with the location of lesions, whereas IgG positivity to toxoplasma at low dilutions predominated.

Keywords : Toxoplasmosis; retinochoroiditis; antibodies.

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