Abstract

PEREZ VERANES, Maiquel et al. Pharmacological treatment of strabismus. Rev Cubana Oftalmol [online]. 2022, vol.35, n.1  Epub Aug 29, 2022. ISSN 1561-3070.

Extraocular musculature surgery has been the standard of care for surgical treatment of strabismus for more than a century. Despite the great technical development of strabismus surgery today, the use of a surgical microscope, the novel design of surgical instruments, the quality of the non-absorbable suture; Advances in anesthetic equipment and drugs, it is not exempt from surgical complications, in addition to the recovery time that the patient needs to return to their social activities, have led to a permanent search for pharmacological treatment for strabismus. The objective of this bibliographic review is to analyze the different pharmacological alternatives available as a treatment for strabismus. For its preparation, full texts and articles in Spanish and English languages were consulted, available in some databases. We conclude that although numerous drugs have been studied, botulinum toxin, which is the best known and used worldwide, followed by bupivacaine. We find others such as IGF I and II (Insuline Growing Factor), capable of generating an effect of reinforcing muscle activity. And others that “weaken” MOE include mAb35-Rubicin, BMP4 (Bone Morphogenic Protein). His research is continuing today.

Keywords : Toxin, mAb35-Rubicina, BMP4 (Bone Morphogenic Protein), IGF I y II (Insuline Growing Factor); Surgery; Strabismus..