Abstract

GONZALEZ GONZALEZ, Félix  and  NICOLAU MENA, Orlando. Hypertensive patients treated with chlorhydrate de metphormine. AMC [online]. 2001, vol.5, n.3. ISSN 1025-0255.

With the aim of evaluating the effect that diminishing of insulinemia exerts on the evolution of the arterial hypertension , a prospective, applied and observational analytical study is carried out at "manuel Ascunce Domenech" Provincial Hospital in a group of patients, from september 1999 to september 2000. Cases were divided into a control group, of 32 patients, and a study group of 32 patients two that received treatment of chlorhydrate of metphormine during 6 months. At the same time , each group was divided into subgruops of 16 patients each: two formed by hipertensive patients with central obesity and the other two formed by hipertensive patients with central obesity and diabetes mellitus. Out of the study universe (n=64), 50% were womwn and the other 50% men from, 25 to 70 years old. The drug effect was evaluated on the values of blood pressure in a group of patients , analyzing the body mass index at the beginning and at the end of the research. It was found decreasing of values and falling away fo blood pressure values and insulinemia in diabeties. The declining of lipidic values in the study gruops treated with this drug is very important.

Keywords : HYPERTENSION [therapy]; METFORMIN [therapeutic use].