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Revista Archivo Médico de Camagüey

On-line version ISSN 1025-0255


FUENTES DIAZ, Zaily; RODRIGUEZ SALAZAR, Orlando; SALAZAR DIEZ, Mabel  and  RODRIGUEZ HERNANDEZ, Orlando. Some neurolytic agents: General considerations. AMC [online]. 2007, vol.11, n.1. ISSN 1025-0255.

Different chemicals have been used for the intentional interruption of the nociceptive vias. The ideal agent should be capable of interrupting selectively only the nervous fibers A-delta and C, but unfortunately all the agents commonly used cause an undiscriminated destruction of the nervous tissue. The neurolytic blocks destroy the nervous fibers with the injection of a neurolytic agent in the subarachnoid space, peridural or directly over the nervous fiber as such. Therefore, the therapeutic model to employ should go deeply into the extreme precaution for not affecting indispensable fibers as the motor ones and the need to relieve or eliminate the nociceptive afferences to improve the quality of life. In spite of its limitations, it is another procedure that allows within a program of evaluation and treatment to offer according to the most advanced criteria on the "worthy death," a different therapeutic for the palliation of the chronic pain, especially in patients with cancer. A review of the neurolytic action mechanism most widely used was carried out and the consequences of its use, so as to provide this tool to all the medical staff.


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