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Revista Archivo Médico de Camagüey

On-line version ISSN 1025-0255


VALERA VALERO, Carlos Alberto et al. Guillian-Barré syndrome and pregnancy. Two cases report. AMC [online]. 2008, vol.12, n.2. ISSN 1025-0255.

Two obstetric patients with Guillian-Barré syndrome are presented, admitted in the intensive therapy room at «Manuel Ascunce Domenech» Educational Hospital, the first one, a 18 years-old expectant mother with 16 weeks of gestation time, admitted by suspects of viral hepatitis, that began with muscular weakness in both lower limbs with walking impossibility. The second expectant mother with 22 years-old and 21 days of the puerperium, came to the hospital with loss of the muscular force in upper and lower limbs, subsequently took the respiratory muscles. This is not an epidemic disease; neither is related to any season of the year. Globally an annual incidence from 0.4 to 1.7 cases for 100 000 people is reported. Pregnancy does not predispose the disease. The main clinical manifestation is the weakness that progresses more or less symmetrically in a period from one to two weeks; affectation in the trunk, the intercostal muscles, the neck and the cranial walls is observed. Support the diagnosis the presence of proteins greater than 0.5% in the cerebrospinal liquid and pleocytosis less than 50 cells by each millimeter. The studies of nerve conduction are of great utility and constitute an indicator in the early diagnosis of the disease.

Keywords : Guillain-Barré syndrome [diagnosis]; steroids [therapeutic use]; neural conduction; electric conductivity; muscle weakness; pregnancy.

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