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Revista Archivo Médico de Camagüey

On-line version ISSN 1025-0255


TARTABULL POUTRIEL, Kiopper; RODRIGUEZ LOPEZ, Aquiles José; NICOLAU PESTANA, Elizabeth  and  GONZALEZ MARTINEZ, Francisco. Circadian rhythm in acute myocardial infarction. AMC [online]. 2009, vol.13, n.1. ISSN 1025-0255.

Background: With the advance of the investigations in cardiology field is attributed special importance to the time of occurrence of acute coronary syndromes; since it has been demonstrated through multiple studies the relationship of these events with time. Objective: To know the behavior of the circadian rhythm in acute myocardial infarction, as well as its probable relationship with diverse epidemic clinical factors, such as: age, sex, risk factors, the effectiveness of thrombolytic therapy and the lethality of the event. Method: A descriptive study in 338 patients discharged from hospital with this diagnosis was conducted at the"Amalia Simoni" teaching clinical-surgical Hospital of Camagüey from January 1st 2002 and December 31st 2006. Clinical histories and protocols of necropsies constituted the source of data, for its collecting a survey model was used, after having filled in it became into the primary registry of this investigation. Results: The 43,20% of patients presented the symptoms between the 06:00 and 11.59 h, patients with antecedents of being smoking, to suffer from high blood pressure and diabetes mellitus began with the symptoms in the first hours of the morning being the night time the most frequent in patients with heart failure and previous antecedents of acute myocadial infarction. Conclusions: The most frequent time of occurrence of the symptoms was on the morning between 06:00-11:59, it were not found differences in this time behavior among both sexes and the analyzed age groups. At equal form morning hours turned out to be of greater lethality and the one of smaller effective response to the thrombolytic therapy.

Keywords : Myocardial infarction; circadian rhytm.

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