Abstract

VAQUEZ CEDENO, Jorge Luis et al. Stevens-Johnson's syndrome: presentation of three cases. AMC [online]. 2015, vol.19, n.3, pp. 271-278. ISSN 1025-0255.

Background: Stevens-Johnson’s syndrome (SJS) is a serious disease, fatal most of the time, which has been considered as a type of erythema multiforme. It is generally caused by medicaments. If it is not diagnosed and treated at appropriate time it can be associated to considerable sequelae and death. Objective: to describe the treatment and evolution of the clinical manifestations of three cases with the diagnosis of Stevens-Johnson’s syndrome admitted in the intensive care unit. Cases presentation: the cases of two female patients and a male patient with the diagnosis of SJS, associated to the use of medicaments, are briefly presented. The treatment consisted of measures of general care for the prophylaxis and treatment of complications for the three cases. The patients were treated with intravenous IgG of national production (intacglobin) and systemic steroids. The three patients improved their condition satisfactorily. Results: the use of intravenous immunoglobulin G in the treatment of these patients stands out; as well as the importance of the treatment of seriously ill patients in an intensive care unit. Conclusions: female sex predominated in the casuistics. The early use of Intacglobin (IgG IV) contributed to a better improvement of the patient’s condition arresting the development of the disease, avoiding complications and decreasing the hospital stay of seriously ill patients.

Keywords : STEVENS-JOHNSON SYNDROME; IMMUNOGLOBULINS, INTRAVENOUS; IMMUNOGLOBULIN G; ADULT; CASE REPORTS.

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