Abstract

LA ROSA, Deyanira et al. Breastfeeding and humoral immune response against tetanus and diphtheria toxoid in children of 2 years old. Vaccimonitor [online]. 2011, vol.20, n.3, pp. 9-13. ISSN 1025-028X.

Since the impact of breastfeeding on the response to vaccination is controversial, we studied the effect of breastfeeding on humoral response to tetanus and diphtheria vaccination in two years old children who have ended the immunization basic stage of the vaccination schedule. Forty-four children were selected, they were then divided into two study groups according to the time they were breastfeeding. Solid phase immunosorbent assays (ELISA) were used to determine concentrations of diphtheria and tetanus antitoxin. After applying the Student test to results, it was proved that exclusive breastfeeding for six months or longer showed an increase in the concentrations of diphtheria antitoxin, while there was no difference of tetanus antitoxin concentrations detected among children exclusively breastfed for six months or more, with those breastfed for lesser periods.

Keywords : Breastfeeding; vaccines; tetanus toxoid; diphtheria toxoid.

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