Abstract

COOLS, Evelien; VAN-DIJCK, Patrick  and  AVONCE, Nelson. Heterologous protein production in the moss Physcomitrella patens. Vaccimonitor [online]. 2017, vol.26, n.2, pp. 66-69. ISSN 1025-0298.

Over the last decades plants have been used for the heterologous production of pharmaceuticals, industrial enzymes and edible vaccines. The moss Physcomitrella patens is considered as an experimental model of choice for basic molecular, cytological and developmental questions in plant biology, as well as an outstanding plant model system for heterologous protein production. Here we use P. patens to produce osmotin, a tobacco protein with fungicidal properties. We have generated a transgenic plant able to synthesize and secrete a biologically active osmotin protein.

Keywords : moss; bioreactor; recombinant protein.

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