Abstract

BARRIO ALONSO, Gloria del; ROQUE QUINTERO, Annele  and  ARIAS, Martha. Estudio comparativo de la capacidad inactivante de distintas colectas de la planta phyllanthus orbicularis. Rev Cubana Plant Med [online]. 2001, vol.6, n.3, pp. 83-86. ISSN 1028-4796.

The authors studied the inactivation of AgsHB by extracts from 2 harvests of Phyllanthus orbicularis, carried out at different times of the year (March/94 and October/94) in 34 positive sera at this marker. These results were compared with those obtained for the harvest of August/93 to know the influence on harvesting time on the presence of the anti-hepatitis B activity of the plant. All the assayed concentrations (100, 50, and 254 mg/mL) reduced the absorbency values in sera, achieving a statistically significant seroconversion to negatives, excepting what happened for concentrations of 25 and 12,5 mg/mL of the harvest of October/94. The quantity of negative sera was proportional to the concentrations used. There were statistically differences between the harvests of August/93 and October/94. These results suggested that alterations may occur in the presence or concentration of the possible active components of P. orbicularis due to the influence of external factors, such as the climatic conditions.

Keywords : PLANT EXTRACTS [therapeutic use]; HEPATITIS B VIRUS [drug effects]; HEPATITIS B [drug therapy.].

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