Abstract

JIMENEZ MARTINEZ, María del Carmen; SEBAZCO PERNAS, Caridad; PEREZ ALEJO, José Luis  and  MARTINEZ MARTIN, Sara M. Evaluation of the ergogenic activity of the natural product called Noni-C^®. Rev Cubana Plant Med [online]. 2013, vol.18, n.3, pp. 479-486. ISSN 1028-4796.

Introduction: Noni-C^® is a natural product that has been registered as a nutritional supplement. It is obtained from the plant Morinda citrifolia L., associated to many demonstrated clinical qualities and traditionally used to fight fatigue. Objective: to determine the ergogenic activity in an experimental model of fatigue in mice. Methods: a model of fatigue was applied in mice, using a Rotarod Ugo Basile model of 7650 variable speed and 7600 constant speed. 6 groups were used: I with saline solution, II with sterile water and propilenglicol and III; IV, V, VI with sterile water, propilenglicol and Noni-C^® at doses of 20, 40, 200 and 400 mg/kg of body weight, respectively. A previous training to mice was conducted in the Rotarod during 3 consecutive days for 1 and 2 hours each day. The final test was done in 2 hours, with change in speed and a constant maximum speed to the end of the time. Results: a significant increase in the resistance to fatigue in seconds was observed in the groups treated with Noni-C^® at doses of 200 and 400 mg/kg with respect to the group treated with saline solution. Conclusions: the product called Noni-C^® showed to have ergogenic activity at increasing resistance to fatigue in Balb/c mice, after a treatment for 14 days with oral doses of 200 and 400 mg/kg.

Keywords : Noni-C^®; Morinda citrifolia L.; fatigue; experimental model; rats.

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