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On-line version ISSN 1028-4818


VERDECIA AGUILAR, Merlin  and  FRIAS VILTRES, Diana Francis. Circadian rhythm of ischemic cerebrovascular diseases. Multimed [online]. 2021, vol.25, n.1, e1179.  Epub Jan 01, 2021. ISSN 1028-4818.


cerebral infarction follows a circadian pattern, the cause of which has not yet been well established.


to characterize the circadian rhythm of ischemic strokes taking into account the sex, the affected territories and the level of consciousness presented by the patient during the onset of the event.


the universe consisted of all patients with cerebral infarction who were included in the database belonging to the International Stroke Trial. The variables sex, irrigation territory and level of consciousness were used. For the study of the circadian rhythm, the MetaCycle package, belonging to the R software, was used.


most of the categories presented a significant circadian rhythm (p <0.05). The time of debut, the male sex, the female sex, the posterior territory, the anterior territory and non-unconscious presented phases of 10.45, 10.42, 10.35, 10.22, 10.67 and 10.46 respectively.


the onset of ischemic strokes presents a circadian rhythm, as do the variables sex, age, anterior territory, posterior territory and unconscious. The unconscious category did not present a defined 24-hour pattern.

Keywords : Ischemic stroke; Circadian rhythm.

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