Abstract

RODRIGUEZ FERNANDEZ, Zenén; GONZALEZ-RODILES HEREDIA, Roswell Enrique  and  CASAUS PRIETO, Arbelio. Recurrent colon cancer: disease free interval and adjuvant treatment. MEDISAN [online]. 2009, vol.13, n.6. ISSN 1029-3019.

Objective: To determine the "disease free interval" and its relationship with the applied adjuvant treatment with healing intention to the operated patients of colon cancer. Methods: a descriptive, observational and prospective study was carried out on the "disease free interval " in 68 patients after having surgical treatment of colon cancer in ¨Saturnino Lora¨ Teaching Provincial Hospital of Santiago de Cuba from 1990 to 2008 that presented tumorous recurrence, diagnosed in outpatient department by means of a posoperative follow up outline during a five year period or more. Results: The monoquimiotherapy with 5-fluoruracilo as adjuvant treatment provided better results in the patients that received 6 therapeutic cycles, because in this group, none repeated before the year of being operated, whereas is the only one that reaches a disease free interval for more than five years. The anatomical localization was not an influential factor in the mentioned interval. Conclusions: The appropriate adjuvant treatment with 5-fluouracilo kept relationship with the long lasting disease free interval. It is imposed to increase the surveillance of the operated patients due to colon cancer with healing intention in the first 2 years of posoperative follow up, because during that biennium most of the recurrences take place in any localization.

Keywords : COLONIC NEOPLASMS; COLONIC NEOPLASMS [therapy]; COLONIC NEOPLASMS [surgery]; NEOPLASM RECURRENCE, LOCAL; CHEMOTHERAPY, ADJUVANT.

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