Abstract

GUZMAN PILETA, Kenia et al. Main clinical-epidemiological characteristics of patients with cystic fibrosis in Santiago de Cuba province. MEDISAN [online]. 2011, vol.15, n.2, pp. 152-161. ISSN 1029-3019.

A descriptive and cross-sectional study was carried out during 2008 in order to determine the main clinical-epidemiological characteristics of 34 patients with cystic fibrosis in Santiago de Cuba province assisted by the Provincial Group of this field. In the case material, the following variables: male sex, yellow skin, residents in Santiago de Cuba municipality, low weight, presenting symptoms and the diagnosis of a disease during the first decade of life and respiratory infection, the latter as main complication, were relevant. Among the symptoms, the most frequent were cough, expectoration, abdominal pain, voracious appetite, as well as the mixed form according to the occurrence type which also was the cause of the major number of admissions. Among the results of some other tests, just for quoting some examples, mild obstructive breathing malfunction, homozygotic DF 508 genetic mutation as well as isolation of the Pseudomonas aeuruginosa in the sputum and Βhemolytic β-streptococcus in the nasopharyngeal exudate were predominant.

Keywords : cystic fibrosis; obstructive breathing malfunction; genetic mutation; Pseudomonas aeuruginosa; hemolytic β-streptococcus.

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