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MEDISAN
On-line version ISSN 1029-3019
Abstract
RODRIGUEZ BRUNET, Marisol et al. Clinical epidemiological aspects of chronic lymphoid leukaemia. MEDISAN [online]. 2011, vol.15, n.3, pp. 330-338. ISSN 1029-3019.
A descriptive and retrospective study of 71 patients with chronic lymphoid leukemia, attended at the Hematology Service from ¨Dr Juan Bruno Zayas Alfonso¨ Teaching General Hospital in Santiago de Cuba was carried out from January, 2001 to November, 2006, in order to identify some clinical epidemiological variables on them, to show the therapeutical variables more used, as well as to assess survival, mortality, and the main causes of the clinical entity. Elderly, male sex, and high risk category related to advanced stage were predominant in the series. The therapeutical schedule of chlorambucil and prednisone was the most used, achieving good results in the majority of the case material. The survival of patients, in general, ranged among 1-5 years, whereas deaths occurred due to disease progression, infectious respiratory processes, pro-lymphocytic transformation, second neoplasias, and strokes.
Keywords : chronic lymphoid leukemia; therapeutical schedules; staging; survival; mortality; Hematology Service.