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MEDISAN

On-line version ISSN 1029-3019

Abstract

RODRIGUEZ ALFARO, Maryenis; GROSS FERNANDEZ, Caridad  and  CASAS GROSS, Sandra. Effectiveness of antiretroviral therapy for patients with Human Immunodeficiency Virus/AIDS in a hospital from Zimbabwe. MEDISAN [online]. 2011, vol.15, n.4, pp. 433-441. ISSN 1029-3019.

A prospective and descriptive research of 171 patients with HIV/AIDS who received antiretroviral therapy from April, 2008 to December, 2008 at Bindura Hospital from Central Mashonaland province (Zimbabwe) was carried out in order to assess its effectiveness. CD4 cells count was taken into account for this. In addition, compliance was determined for a 6-month period after being prescribed and patients were monitored during the study stage. Cases started to be treated in the first two weeks with double combination (estavudina + lamivudina) and triple combination (estavudina + lamivudina + nevirapine) 95,32 % of patients followed the treatment, 90,06 % had an appropriate CD4 cells count, and 83,60 % showed clinical improvement, in which case it was inferred that therapeutic effectiveness depended on the grade of medical prescription compliance and pharmaceutical staff decisively contributed to the obtaining of those good results.

Keywords : Human Immunodeficiency Virus; AIDS; antiretroviral therapy; Zimbabwe.

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