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MEDISAN
On-line version ISSN 1029-3019
Abstract
CAVEDA GIL, Ángel Ernesto; NAPOLES MENDEZ, Danilo and COUTO NUNEZ, Dayana. Two therapeutic modalities in the active childbirth. MEDISAN [online]. 2011, vol.15, n.8, pp. 1040-1048. ISSN 1029-3019.
A new therapeutic plan was used for the active childbirth, based on sublingual misoprostol use, aimed at evaluating its effectiveness and safety. For this, a phase III pragmatic clinical trial was carried out with specific characteristics that included pregnant women taken as controls and treated according to the standards in that case, as well as 2 experimental groups (1 and 2) in whom the active and non invasive procedure proposed for the study was used. The sample was formed by 600 pregnant women assisted at the Childbirth Service of "Mariana Grajales Coello" Gynecological and Obstetrical Hospital in Santiago de Cuba from June, 2009 to the same month of 2010. In the 2 last groups, both the time of average childbirth and the volume of calculated bleeding were smaller than in the first one, and it was concluded that misoprostol at the doses and administration route proposed turned out to be more effective and safe than oxytocin.
Keywords : pregnancy; misoprostol; oxytocin; active childbirth; maternal hospital.