Abstract

CUEVAS MORILLO, Claudia Carolina; RODRIGUEZ CONSTANTIN, Alejandro; RODRIGUEZ BEYRIS, Reynaldo Pedro  and  ROMERO GARCIA, Lázaro Ibrahín. Clinical and epidemiological characterization of patients with hepatitis C under hemodialysis and associated prognosis factors. MEDISAN [online]. 2012, vol.16, n.5, pp. 669-678. ISSN 1029-3019.

An observational and analytic case-control study, of all the terminally ill patients with chronic renal failure exposed to purifying treatment with hemodyalisis who didn't suffer hepatitis C at the beginning of the investigation, assisted in "Dr. Juan Bruno Zayas Alfonso" General Hospital in Santiago de Cuba was carried out from January, 2009 to December, 2010, with the objective of characterizing them according to clinical and epidemiological variables of interest and determining the incidence of hepatitis C virus in both study groups, keeping in mind the different prognosis factors. A logistical regression multivariate analysis was applied to identify these factors and the causative influence in the infection by the mentioned virus. Male sex (72.0 %), the age group 45-54 years (21.3 %) and hypertensive (37.3 %) and diabetic (18.7 %) nephropathies prevailed in the series, as the fundamental causes of the disease. Among the main prognosis factors there were the previous hepatic illnesses (OR = 4.80), the exposure to hemoderivatives (OR=1.46) and the reuse of dialysers (OR=1.38).

Keywords : hepatitis C virus; minal chronic renal failure; hemodyalisis; epidemiological risk factor; secondary health care.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )