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On-line version ISSN 1029-3019


ESTRADA PEREIRA, Gladys Aída; MARQUEZ FILIU, Maricel; GONZALEZ HEREDIA, Eugenia  and  HERNANDEZ ALVAREZ, Galina. Application of liquid nitrogen in the treatment of patients with oral leukoplakia. MEDISAN [online]. 2013, vol.17, n.4, pp.669-676. ISSN 1029-3019.

A descriptive and cross-sectional study was carried out in 200 patients with oral leukoplakia, attended in the stomatology department of the Polyclinic of Specialties in "Saturnino Lora Torres" Provincial Teaching Clinical Surgical Hospital of Santiago de Cuba, from September 2007 to the same month of 2012, in order to evaluate the therapeutic effects of liquid nitrogen in treating this condition. This coolant was used in the surgical removal of the lesion and contributed to a good regeneration of affected oral tissues in the shortest time possible. With this purpose repeated interventions of sudden cooling were applied, as well as slow and spontaneous thaws with excellent results in the members of the case material. This cryogenic substance was effective in the mucosal epithelium by its anesthetic, antimicrobial, anti-infective, healing and immunologic properties, allowing a quick and less painful cure, without risk or complication, and safe for oral tissues, which prevented the occurrence of residual scars.

Keywords : liquid nitrogen; surgical removal; cryothermal method; cryogenic substance; secondary health care.

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