Abstract

KUDER, Haifah et al. Hemoglobin S detection in neonates of the Venezuelan state of Carabobo. MEDISAN [online]. 2014, vol.18, n.8, pp. 1121-1126. ISSN 1029-3019.

A descriptive study of 129 neonates of both sexes, born in the Neonatology Unit of a Public Health Center from Puerto Cabello city, Venezuelan state of Carabobo, was carried out from January, 2012 to June, 2013, in order to detect early newborns with hemoglobin S. In the series the feminine sex prevailed (51.9%). The electrophoresis technique was used and normal hemoglobin (Hb A) was found in 91.5%, as well as electrophoretic patterns of abnormal hemoglobin compatible with Hb S in 8.5%. Of the 11 positive cases, 90.9% corresponded to Hb SA and 9.1% to Hb SS. The detected hemoglobin SA and SS frequency, even when diagnostic results could not be established, represented a warning to implement the early detection, which conducted to a program of early prevention, and to prophylaxis from the first months of life

Keywords : hemoglobinopathies; hemoglobin S; sickle cell anemia; electrophoresis; Venezuelan state of Carabobo.

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