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MEDISAN
On-line version ISSN 1029-3019
Abstract
GONZALEZ TUERO, Jaime Humberto. Effect of the saline slime of Guantánamo in the scaring in a second intention in rats. MEDISAN [online]. 2014, vol.18, n.9, pp. 1195-1203. ISSN 1029-3019.
A preclinical, experimental and analytical study was carried out, in 100 Sprague-Dawley rats to determine the effects of the saline slime from Guantánamo in the scaring for second intention in a model of incisional wound, by means of the simultaneous control to them. They were distributed in 4 groups: a study group and 3 control groups; the first ones were treated with slime and the second ones were treated with 0,9% NaCl; 4,0% NaCl and Hebermin®, respectively. It was verified that the wounds healed quicker with slime and that there was an effective acute inflammatory reaction when reducing the edema and the devitalized tissue, besides stimulating the angiogenesis, fibroplasia and reepitelization. It was concluded that the saline slime from Guantánamo has more effective healing properties than Hebermin® and 4,0% NaCl
Keywords : Sprague-Dawley rats; incisional wound; scaring of wound; slime; Guantánamo saline.