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On-line version ISSN 1029-3019


ESTRADA PEREIRA, Gladys Aída; DIAZ FERNANDEZ, José Manuel; MARQUEZ FILIU, Maricel  and  AGUERO DESPAIGNE, Liliet Antonia. Oncospecific therapies in patients with herpes simplex virus. MEDISAN [online]. 2017, vol.21, n.2, pp.161-168. ISSN 1029-3019.

A descriptive and cross-sectional study of 25 patients with cancer infected by the oral herpes simplex virus was carried out. They had the immunologic system damaged due to oncospecific treatment, assisted in the stomatological service of the Specialties Polyclinic of "Saturnino Lora Torres" Teaching Clinical Surgical Provincial Hospital in Santiago de Cuba, from January, 2014 to the same month in 2016, in order to evaluate the results of the clinical and cytopathologic diagnosis of this disorder. In the case material the male sex and pain as clinical symptomatology, the vermilion of the lower lip as the place of more incidence and chemotherapy as the therapeutic modality of this viral agent higher reactivation prevailed. The exfoliative cytology confirmed the presence of multinucleous giant epithelial cells with bodies of intranuclear inclusions and infected cells necrosis, respectively, being these the most significant microscopic findings

Keywords : oral herpes simplex virus; clinical and cytopathologic diagnosis; oncospecific therapy; body of intranuclear inclusion; multinucleous giant epithelial cell; necrosis of infected cell; secondary health care.

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