Abstract

GONZALEZ ALVAREZ, Yusimí et al. Humoral immune markers and their association with the psychoemotional state of patients with systemic lupus erythematosus. MEDISAN [online]. 2017, vol.21, n.11, pp. 3251-3260. ISSN 1029-3019.

A descriptive and cross-sectional investigation of 154 patients, aged 20 to 59, with systemic lupus erythematosus assisted in the Autoinmune Diseases Provincial Service of "Arnaldo Milián Castro" Clinical Surgical Hospital in Santa Clara (Villa Clara), was carried out from June, 2014, to May, 2015, aimed at determining the association of the humoral immune markers with the psychoemotional state, as predictive factors of decompensating events in these affected patients.  In the series, there was a prevalence of the young adults, female sex, white color of the skin, workers as occupation, hypertension as personal pathological history and coffeeholism.  At the same time, the detected disorders constituted humoral immune and inflammatory markers to predict possible activity of the disease in the subclinical stage and it was strongly associated with the presence of emotional disorders (anxiety and depression) in the patient, what can suggest an imminent future acute crisis of the disease

Keywords : systemic lupus erythematosus; biomarkers; autoinmune inflammatory diseases; psychoemotional state.

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