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MEDISAN
On-line version ISSN 1029-3019
Abstract
MENDO ALCOLEA, Neity et al. Adverse reactions to antirretroviral drugs in patients with the human inmunodeficiency virus. MEDISAN [online]. 2018, vol.22, n.8, pp.674-682. ISSN 1029-3019.
A descriptive and cross sectional study of 40 patients with HIV belonging to the Teaching Polyclinic "Frank País García" in Santiago de Cuba was carried out with the aim of identifying the adverse reactions to antirretroviral drugs during the first semester of 2018. Most of the notifications were carried out by specialists in Comprehensive General Medicine (61,4%) in the case material, followed by those of Internal Medicine and Licentiate in Nursing (8,8 and 17,6%, respectively); also, among the predominant adverse effects there were nauseas, migraine and sickness, fundamentally with the therapeutic schemes constituted by lamivudina-zidovudina-nevirapina and zidovudina-nevirapina-efavirenz. It is concluded that during antirretroviral treatment most of these reactions were classified as definitive, independently of the prescribed therapeutic scheme and the concomitant diseases.
Keywords : HIV; antirretroviral drugs; adverse reaction; pharmacosurveillance; primary health care.