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MEDISAN
On-line version ISSN 1029-3019
Abstract
AQUIN ROLL, Carlos; ASTORGA ZAYAS, Laina María and GONZALEZ GARCIA, Daylín Elizabeth. New aspects on digitalis toxicity. MEDISAN [online]. 2019, vol.23, n.2, pp. 284-307. ISSN 1029-3019.
Digitalis are drugs with the capacity of increasing myocardial contractility (inotropic positive agents) which have carried out an important role in the treatment of heart failure; their inappropriate use can bring severe complications to the patient, even, to death. The most important in these complications is the digitalis toxicity, originated by the overdose of these drugs, caused by the combination of the inhibitory effect in the nodal conduction and stimulation on the individual atrial and ventricular fibers. Due to the frequent use of these medications at all levels of medical care and to the difficulty in diagnosing this complication caused by the complexity of their clinical pattern and of their electrocardiographic expression, an exhaustive literature review was carried out on the topic to give a wide information that allows an appropriate care to the patients with this diagnosis.
Keywords : drug; myocardial contractility; digitalis; digitalis toxicity.