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MEDISAN

On-line version ISSN 1029-3019

Abstract

GONZALEZ AGUILERA, Julio César; CABRERA LAVERNIA, Jorge Omar; MARTI GARCES, Gloria Mabel  and  PEREZ ARTIMEZ, María Elena. Seric albumin as prediction factor of multiple failures of organs in patients with secondary diffuse peritonitis. MEDISAN [online]. 2020, vol.24, n.4, pp. 627-640.  Epub July 24, 2020. ISSN 1029-3019.

Introduction:

Seric albumin constitutes one of the parameters used to predict the risk of complications in patients surgically intervened.

Objective:

To evaluate the utility of seric albumin as prediction factor of multiple failure of organs in patients with secondary diffuse peritonitis.

Method:

An observational, cohorts analytic study of 54 patients with secondary diffuse peritonitis was carried out, they were assisted in the Intensive Cares Unit of Carlos Manuel de Céspedes University General Hospital in Bayamo, Granma, during 2016. The marker variable of prediction was the multiple failures of organs that was evaluated with the Sequential scale Organ Failure Assessment.

Results:

In the 37.7 % of patients multiple failure of organs was developed; also, the average value of seric albumin at admission (standard deviation) was 30.3 g/L (+ 3.4) in patients with this disorder and 33.2 g/L (+ 4.1) without this disorder (p=0.012). The relative risk of multiple failure of organs was 1.9 (CI: 95 % 1.1-3.2) with albumin of 30 g/L or less. In the multivariate analysis seric albumin constituted an independent factor of multiple failure of organs along with APACHE II index; while the area under the curve receiving operator presented a value of 0.7 when the discriminative capacity of the albumin was considered to predict if the multiple failure of organs was not present and 0.2 to predict its development.

Conclusions:

Seric albumin is useful as prediction factor of multiple failure of organs in patients with secondary diffuse peritonitis.

Keywords : seric albumin; peritonitis; multiorganic failure; prediction factor; mortality due to peritonitis; Intensive Cares Unit.

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