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On-line version ISSN 1029-3019


COLUMBIE REGUEIFEROS, Justa Carmen et al. Variation of tumoral biomarkers in patients with chronic respiratory diseases. MEDISAN [online]. 2020, vol.24, n.5, pp.836-846.  Epub Oct 05, 2020. ISSN 1029-3019.


Biomarkers are biological or biochemical substances which emerge as a response of the organism on certain types of tumors and which reflect the stage or degree of them.


To determine the association of tumoral markers with the chronic respiratory events.


A descriptive and cross-sectional study of 306 patients diagnosed with chonic respiratory diseases and assisted at the Pneumology community outpàtients from Santiago de Cuba province was carried out from January, 2014 to December, 2018.


Male sex and ages between 60 o 69 years as well as interstitial diseases, chronic bronchitis and the chronic obstructive pulmonary disease predominated in the series. Likewise, radiological studies were also important for detecting neoplasic processes, mainly with the use of the axial computerized tomography. On the other side, markers presenting altered values were the CYFRA 21.1 y el CA 72.4, so that its association with the chronic respiratory processes.


Tumoral biomarkers are an usefull tool in the follow-up of patients with malignant neoplasies, but also they show altered values in the presence of different chronic respiratory diseases, which doesn´t mean there is a malignant process.

Keywords : chronic respiratory diseases; tumor biomarkers; pneumology service.

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