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On-line version ISSN 1029-3019


INFANTE CEDENO, Reydienis Ricardo; IBAR SANCHEZ, Elizbieta  and  GARCIA CESPEDES, María Eugenia. Predictive factors for bone metastasis in patients with prostate cancer. MEDISAN [online]. 2023, vol.27, n.5  Epub Oct 31, 2023. ISSN 1029-3019.


Prostate adenocarcinoma is considered one of the most frequent neoplasms in men over 60 years, and bone metastasis constitutes one of the complications with the worst prognosis.


Estimate the predictive factors for bone metastasis in patients with prostate cancer.


An analytic study of 73 patients with prostate cancer was carried out. They were assisted at Conrado Benítez Cancer Hospital in Santiago de Cuba during 2018-2022. The variables analyzed included: age, skin color, clinical manifestations, onset time of bone metastasis, degree of cellular differentiation, prostate-specific antigen level and imaging diagnosis.


In the series there was a prevalence of the 60-69 age group (50.7%) and the average age was 67 years; also, dark skinned patients, bone pain as more frequent symptom and imaging diagnosis of bone metastasis by computerized axial tomography prevailed (48.0%). A proportional increase of prostate-specific antigen values and Gleason punctuation was observed in relation to the metastasis onset.


The predictive factors for estimating the presence of bone metastasis in patients with prostate cancer are the advanced age, black skin color and prostate-specific antigen values above 20 ng/mL.

Keywords : prostate cancer; bone metastasis; predictive factor; prostate-specific antigen.

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