Abstract

MINOSO GALINDO, Isa; BEQUER MENDOZA, Leticia  and  GOMEZ HERNANDEZ, Tahiry. Zinc supplementation favours intrauterine growth in diabetic rat fetuses. Medicentro Electrónica [online]. 2023, vol.27, n.4  Epub Dec 01, 2023. ISSN 1029-3043.

Zinc deficiency may be a mediating factor in fetal growth disorders in the offspring of diabetic pregnant women. The objective was to determine the influence of a zinc supplement on external body and craniofacial morphometry in diabetic rat fetuses with moderate hyperglycemia. During gestation, diabetic and control rats were orally supplemented with zinc sulphate (50 mg/kg bw) or received no treatment. The fetuses descendants of the supplemented diabetic group had levels similar to the control ones in the determined somatic growth variables. Zinc supplementation to diabetic rats favoured intrauterine growth in fetuses. The results of this research constitute a contribution to elucidate zinc requirements that allow preventing fetal growth disorders in the offspring of diabetic pregnant women.

Keywords : diabetes mellitus, experimental; fetal growth retardation; zinc.

        · abstract in Spanish     · text in Spanish     · Spanish ( pdf )