Abstract

RUIZ LOPEZ, Ana Isabel; PEREZ MESA, Juan Carlos; BORREGO CHI, Yanexy  and  CRUZ BATISTA, Yanelis. Testosterone and Prostate Specific Antigen in Patients with Prostatic Carcinoma. Holguín Province. 2013-2015. ccm [online]. 2017, vol.21, n.3, pp.720-733. ISSN 1560-4381.

Introduction: the increase of oncological diseases is taking on more and more lives in the world and in Cuba without distinction of race and age. At present this disease occupies an increasingly preponderant place in the world and is already the leading cause of death. Prostate cancer is the second leading cause of death in men worldwide and ranks fifth in the cause of this condition, with an estimated 30.000 new cases per year in the world. Objective: to characterize the serum behavior of testosterone and specific prostatic antigen in patients with prostatic carcinoma, from 2013 to 2015 in the province of Holguín. Methods: a retrospective cross-sectional descriptive study was carried out. The universe consisted of 104 patients diagnosed with prostate cancer at the Cancer Center of Vladimir I. Lenin Hospital. Descriptive indicators of the type of asolute, percentage, mean, standard deviation and coefficient of variation were used. The testosterone and specific prostatic antigen numbers were distributed in age groups and their serum values ​​were associated. Results: testosterone levels remained normal in 97.12% of cases, while levels of prostate specific antigen increased significantly in 85.57%. The age group with the most patients presented in both cases was 61 to 71 years. Conclusions: this research confirmed that this neoplasia mainly affects the elderly and raises the specific prostatic antigen. The program established for an early diagnosis of this disease is necessary to be applied, which raises the possibility of a timely and effective treatment that facilitates the chances of cure and control of this illness.

Keywords : testosterone; specific prostate antigen; carcinoma; prostatic neoplasms.

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