Abstract

OVIES CARBALLO, Gisel; MARTINEZ DE SANDELICES, Alicia; MONTEAGUDO PENA, Gilda  and  SARDINAS DIAZ, Irelys. Genetic bases of polycystic ovary syndrome. Rev Cubana Endocrinol [online]. 2011, vol.22, n.3, pp.255-265. ISSN 1561-2953.

The syndrome of polycystic ovaries is the endocrine disorder involving more the reproductive sphere of the woman in fertile age, its causes are unknown with accuracy, but most of experts coincide in propose that it is a multifactor entity where the genetic factor more and more have a great significance. In past years, it has been possible to identify some genes involved in the pathogenic processes of this syndrome and among the more important are included those codifying for enzymes of the steroidogenesis, for the insulin receptor and other hormones related to the insulin action, as well as the gonadotropins and its receptors, features that are the aim of present review.

Keywords : polycystic ovary syndrome; genetics.

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