Abstract

LOURIDO PEREZ, Hetzel de la C; MARTINEZ SANCHEZ, Gregorio; FLEITAS VIGOA, Danay de la C  and  FERNANDEZ BECERRA, Joaquín. Salivary redox environment: comparison between patients suffering from periodontal disease and periodontal healthy patients. Rev Ciencias Médicas [online]. 2009, vol.13, n.2, pp.123-134. ISSN 1561-3194.

Aimed at studying Salivary Redox Environment of the patient suffering from the inflammatory periodontal disease and healthy patients from the periodontal point of view an observation, cross-sectional, a cases and controls study was carried out during July 2006-June 2007 in Pinar del Rio. The universe was comprised of 35 individuals; no sampling was applied; and two groups were formed, “Study” which included affected patients and “Control” periodontally healthy patients.  Both groups were interviewed and a oral and dental examination was performed.  Data were collected in a Data Processing Notebook.  A sample of saliva was taken and kept refrigerated at -20º C to conduct a biochemical analysis with a HITACHI automatic analyzer. The statistical process outliers values, Shapiro-Wilks, Students’s test, Pearson´s correlation coefficient were calculated, all of them at 95 % of certainty. The existence of an imbalance in the Patient’s Redox Environment respect to healthy patients was observed. Mean values were significantly higher than the Avanced Products of Protein Oxidation in the patients of the “Study” respect to those in “Control” and mean values were significantly higher in the Reducing Capacity of the Ferro-Iron in “Control” patients compared with “Study”, determining that the Advanced Products of Protein Oxidation and the Reducing Capacity of the Ferro-Iron were  the variables of the major diagnostic value for periodontal disease.

Keywords : Oxidative stress; Periodontal disease; saliva.

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