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Revista de Ciencias Médicas de Pinar del Río
On-line version ISSN 1561-3194
Abstract
HERNANDEZ ROJAS, Ana Lidia; HERNANDEZ DIAZ, Aida Rosa; DEL CAMPO MARTINEZ, Sissy and LESCALLE ORTIZ, Yoleiny de la Caridad. Effectiveness of the application of Heberprot-P in the elderly with diabetic foot ulcers. Rev Ciencias Médicas [online]. 2021, vol.25, n.2 Epub Apr 01, 2021. ISSN 1561-3194.
Introduction:
Heberprot-P is a treatment that has proved to be effective in the treatment of diabetic foot ulcers.
Objective:
to characterize the evolution of the elderly with diabetic foot ulcers treated with Heberprot-P in Pinar de Rio.
Methods:
an observational, descriptive, longitudinal and retrospective study was carried out in the elderly treated with Heberprot-P for presenting diabetic foot ulcers in the period 2017-2020. The target group comprised 140 patients, and all of them were studied. Descriptive statistics was applied using absolute and relative percentage frequencies.
Results:
it was found a predominance of female patients (55,72 %), of the age group between 60 and 69 years (60 %) and with neuro-infectious diabetic foot (67,14 %). Ulcer infection was detected in 10 patients (7,1 %) and was associated with lack of granulation (p=0,003; OR=16.11; 95%CI=1.90-726.03). Amputation was required in 13,6 % of patients. An association was found between non-granulation and the requirement for amputation (p<0,05); 37,9 % of the patients presented some adverse response to the administration of Heberprot-P.
Conclusions:
the treatment with Heberprot-P showed encouraging results. The presence of adverse events was relatively high, being these of low repercussions, which ratifies Heberprot-P as an effective and safe treatment to accelerate the healing of diabetic foot ulcers and prevent the need for amputation.
Keywords : DIABETIC FOOT; DIABETES MELLITUS; EPIDERMAL GROWTH FACTOR; AMPUTATION; PERIPHERAL VASCULAR DISEASES.