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Gaceta Médica Espirituana
On-line version ISSN 1608-8921
Abstract
SALCEDO REYES, Caridad et al. Severe sepsis and septic shock in the Intensive Care Unit of José Martí Pediatric Hospital of Sancti Spíritus. Gac Méd Espirit [online]. 2015, vol.17, n.1, pp. 25-34. ISSN 1608-8921.
Background: severe sepsis and septic shock are one of the causes of morbidity and mortality in the pediatric population worldwide. There has been an increase in patients admitted with these stages of sepsis in recent years in the Pediatric Intensive Care Unit of Sancti Spíritus. Objective: to describe the clinical and epidemiological characteristics of severe sepsis and septic shock in the Pediatric Intensive Care Unit of Sancti Spíritus from 2005 to 2008. Methodology: a retrospective study of patients admitted to the Pediatric Intensive Care Unit of Sancti Spíritus with severe sepsis and septic shock in the studied period with the variables age, sex, risk factors for sepsis, place of reference to the Intensive Care Unit, stage of sepsis, targeting, multiple organ dysfunction, used treatment and discharge status. Results: 32 patients were admitted with severe sepsis stadium and septic shock (43.9 %); most affected were children under one year (62.5 %), less than 3 months (37.5 %) and underlying chronic illness (37.5 %). 90.6 % were referred from the emergency rooms. The focus of infection in the respiratory, gastrointestinal apparatus and unfocused infection prevailed. Most of the patients received fluid between 20 and 40 ml/kg in the first hour, the use of antibiotics and vasoactive drugs was appropriate. 75 % progressed to multiorgan dysfunction and 46.88 % died, this accounted for 27.8 % of hospital mortality. Conclusions: the mortality from severe sepsis and septic shock is high, die 1 for each 2.1 patients.
Keywords : severe sepsis; septic shock; systemic inflammatory response syndrome.