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Revista Cubana de Angiología y Cirugía Vascular

On-line version ISSN 1682-0037

Abstract

FEBLES SANABRIA, Ridel Jesús et al. Microbiologic characteristics of patients with diabetic foot ulceration. Rev Cubana Angiol Cir Vasc [online]. 2021, vol.22, n.3  Epub Dec 01, 2021. ISSN 1682-0037.

Introduction:

Diabetic foot ulcer infections are common, complex, high cost and are the leading cause of non-traumatic lower extremity amputation.

Objective:

To identify the microorganisms isolated to estimate both the sensitivity to antibiotics and the coincidence between empirical treatment and microbiological results in patients with diabetic foot ulcers.

Methods:

A descriptive-retrospective investigation was performed. The study population consisted of 210 patients admitted to the University Hospital "Comandante Faustino Pérez Hernández" of Matanzas between June 2017 and June 2020. The output variables were the frequency and type of germ, the number of germs per ulcer, the sensitivity for each type of antibiotic, and the percentage of coincidence between the empirical treatment and the microbiological result.

Results:

A total of 259 germs were identified and 1.23 germs per ulcer were observed. The 62.5% of the germs found were Gram negative, but the most represented germ was Staphylococcus aureus. Of the Staphylococcus aureus, 58.8% were resistant to methicillin. Vancomycin and linezolid were effective in 100% of Gram positives. Amikacin was the most effective antibiotic for Gram-negatives. Agreement between empirical treatment and antibiogram result was observed in 27.6% of patients.

Conclusions:

An appropriate microbiological diagnosis of diabetic foot ulcers is necessary to identify the germs present in the lesions and to design adequate antimicrobial therapy algorithms.

Keywords : diabetic foot ulcer; infection; microbiological culture; germs; antibiotic therapy; empirical treatment.

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