Abstract

SANTOS MUNOZ, Leidy; PERDOMO DELGADO, Johann  and  GONZALEZ PLA, Evelyn Anie. Behavior of adverse reactions caused by natural products: Matanzas 2003-2008. Rev. Med. Electrón. [online]. 2009, vol.31, n.6. ISSN 1684-1824.

The usage of natural medicines is essential in the medico-pharmacological treatment nowadays. Our objective was evaluating behavior of the adverse reactions reports to natural medicines at the province of Matanzas during the period between 2003 and 2008. We carried out a longitudinal, retrospective, observational study. We considered as eligible to this study a universe formed by all the reports of suspected adverse reactions to phytomedicines recorded during the referred period. There was predominance in the frequency of adverse reactions to medicines prepared with Garlic ( Allium sativum L. ), Eucalyptus ( Eucalyptus sp. div. ) and Sour Orange ( Citrus aurantium L.); being these reactions light or moderated, and affecting mainly digestive system and skin. There were reported adverse reactions with the usage of natural products in the studied period, being more frequent the reactions classified as light according to their seriousness, and as probable according to the causality relation, highly affecting the digestive system and skin.

Keywords : MEDICINE, TRADITIONAL ; PHYTOTHERAPY [adverse affects]; PHYTOTHERAPY [statistics & numerical data]; DRUG TOXICITY [classification]; DRUG TOXICITY [etiology]; GARLIC [adverse effects]; EUCALYPTUS [adverse effects]; CITRUS AURANTIUM [adverse effects]; DIGESTIVE SYSTEM [drug effects]; SKIN [drug effects]; PHARMACOEPIDEMIOLOGY [methods]; LONGITUDINAL STUDIES ; RETROSPECTIVE STUDIES ; OBSERVATIONAL STUDIES ; HUMANS.

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