Abstract

JAUMA ROJO, Ariel Jesús et al. CEROLOGICAL INMUNE RESPONSE IN INMUNE COMPROMISED CHILDREN TREATED WITH THE ANTI HEP-B CUBAN VACCINE. Rev haban cienc méd [online]. 2009, vol.8, n.2. ISSN 1729-519X.

The infection for the virus of the Hepatitis B (VHB) it constitutes a problem of world health. Was carried out a study of the specific immunogenicity of the Cuban vaccine HEBERBIOVAC - HB in inmunedepressed children. Children were selected assisted in our service and a group of healthy children as control, without antecedents of being infected by the VHB. The study was carried out to patient and controls to the year of the last dose to determine the titles of antibodies reached by means of the method UMELISA and to know the hipersensibility answer slowed in alive by means of the cutaneous test, evaluating this way qualitatively the cellular immune answer. It was observed that the patient inmunedepressed responded appropriately to the vaccine against the hepatitis B and that after one year of having immunized most maintained the protection, although always with answer levels below the group control with differences statistically significant.

Keywords : hepatitis B; vaccine; immunogenicity; inmunedepressed.

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