Abstract

DIAZ TOLEDO, Manuel et al. Chemotherapy in avanced lung cancer in patients of 60 years and older at hospital benefico juridico (2008-2011). Rev haban cienc méd [online]. 2014, vol.13, n.2, pp.227-237. ISSN 1729-519X.

Introduction: lung cancer is one of the most frequent malignant diseases generally diagnosed at advanced stages, where the main treatment is Chemotherapy. Objective: to characterize the clinical - radiological evolution of 60 years old and older patients suffering from lung cancer not small cells in III B and IV stages, who were treated with polychemoterapy. Materials and Method: a descriptive, retrospective study was done in Benéfico Jurìdico Hospital from January 2008 to December 2011. The sample was composed of 54 patients whose information was obtained from their clinical records and Tumor Committee records. Social demographic and clinical variables studied were: Sex, age, tumor stage, clinical symptoms, general conditions, radiological evolution, and general response to treatment. The higher percentage of studied patients was in the group of 60 to 69 years, and the male sex stood out. Results: a 66.7 % of the sample ware men and the highest rate (65%) were between 60 and 69 years old. A 55.5 % of all cases were classified in a IV stage. There was a significant improvement of the dyspnea, the lost of weight, cough, expectoration and thoracic pain after treatment. In an III B stage, before and after treatment, degree of activity got worse after treatment, prevailing degree of activity 2. In both stages the stable illness prevailed as a radiologic response. Conclusions: lung carcinoma still being more frequent in over 60 years old men. In more than a half of all cases it is diagnosed at advanced stages, were chemotherapy occasionally is able to improve the symptoms, with a poor influence on the degree of activity. Stability, as radiological response, prevailed.

Keywords : lung cancer; clinical stage; clinical and radiological evolution.

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