Abstract

GARCIA PARRADO, Josué et al. Upgrade of the control system of a 75 L bioreactor for the fermentation of bacteria and yeasts. EAC [online]. 2021, vol.42, n.3, pp. 93-104.  Epub Dec 11, 2021. ISSN 1815-5928.

The Center for Genetic Engineering and Biotechnology (CIGB) of Camagüey has a Chemap 75 L bioreactor in the Technological Development Plant, that presents operational difficulties due to an obsolete control system. The present work shows the modernization of the same using technology Siemens and Mettler Toledo. The substitution of the SattCon15 Programmable Logic Controller (PLC) for an S7-300 and the addition of an operator panel TP177B and two M400 T2 transmitters for the measurement of pH and DO are presented. 23 functions are programmed following a strict execution scheme by priorities, five control loops for the variables to be controlled in the process and the possibility of manual and automatic operation. It uses a system of confirmation messages to the user, warning messages and alarms as elements to provide greater reliability and security to the system. The cellular growing, viability and purity results of several fermentation performed are presented showing a control system which complies with the biotechnology industry demands.

Keywords : bioreactor; modernization; control system; PLC.

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