Abstract

GUIBERT TOLEDANO, Zoila Marlene et al. Pregnancy and puerperium in patients with systemic lupus erythematosus. Update. Rev Cuba Reumatol [online]. 2013, vol.15, n.2, pp. 71-75. ISSN 1817-5996.

Systemic lupus erythematosus is known to occur predominantly in women and in their childbearing years. When pregnancy occurs, an increased exposure to oestrogens is expected. Given the known deleterious effects of exposure to oestrogens in systemic lupus erythematosus, pregnancy would reasonably be expected to have an overall negative impact on its course and progression. The impact of pregnancy on lupus disease has been investigated but remains controversial, especially with regard to the incidence of disease y exacerbations during gestation. In contrast, the impact of systemic lupus erythematosus on pregnancy is more clearly understood. Women with lupus disease are not less fertile than unaffected women, but fetal outcome in lupus pregnancy is characterized by higher rates of fetal loss, preterm delivery and intrauterine growth restriction. Post-partum damage accrual significantly increased after pregnancy. It is very important to take into account the role that some features have in systemic lupus erythematosus and pregnancy: disease management, family planning counselling and appropriate patient education in order to prevent the thoroughly described adverse maternal and fetal outcomes pregnant lupus patients may experience.

Keywords : systemic lupus erythematosus; pregnancy; post-partum.

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