Abstract

TORRES LIMA, Ana María; HERNANDEZ CUELLAR, María Victoria  and  RODRIGUEZ TORRES, Ana Yolanda. Immune System and pregnancy: topics in both healthy women and rheumatic patients. Rev Cuba Reumatol [online]. 2013, vol.15, n.2, pp. 76-82. ISSN 1817-5996.

Immune system's tolerance to semi-allogenic antigens during pregnancy is a particular case of response, very efficient in order to maintain the safety of binomius mother/foetus. In this review we emphasizes in those immunological and hormone mechanisms which are involved in tolerance to pregnancy. We also focus in patients with rheumatic autoimmune diseases, in which immunological tolerance mechanisms are broken as part of the pathogenesis of their diseases, whose pregnancies could ameliorate or worsened their conditions, and which recommendations would be usefully for these patients in order to have healthy pregnancy and babies.

Keywords : pregnancy; immunological tolerance; rheumatic diseases.

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