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Revista Cubana de Reumatología
On-line version ISSN 1817-5996
Abstract
BERMUDEZ MARRERO, Witjal Manuel et al. Systemic Lupus Erythematosus, Ten years of follow up. Rev Cuba Reumatol [online]. 2019, vol.21, n.2 Epub Aug 01, 2019. ISSN 1817-5996.
Introduction:
Systemic Lupus Erythematosus is a relatively frequent disease of universal distribution. Its incidence varies according to the characteristics of the studied population such as age, gender and ethno. It is a chronic and autoimmune disease, which cause is not clear at all.
Objective:
to characterize clinically and epidemiologically the patients with systemic lupus erythematosus.
Methods:
A descriptive investigation of 112 patients with diagnosis of systemic lupus erythematosus assisted at Arnaldo Milián Castro University Hospital was carried out from January 2008 to December 2017.
Results:
patients between 30 and 39 years of age were the most representative with a higher incidence in the female sex. High blood pressure prevailed as previous history and coffee as toxic habit. There was a higher affection of the osteomyoarticular system followed by skin and mucosa. The combination of Prednisone and Azathioprine was the most used treatment. Infections were the main cause of death.
Conclusions:
systemic Lupus Erythematosus is present with major frequency in female young patients, with a high risk of systemic affection as well as presenting a life-threatening evolution secondary to infections.
Keywords : systemic lupus erythematosus; autoimmune; autoantibodies; aoutoantigens.