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Revista Cubana de Reumatología
On-line version ISSN 1817-5996
Abstract
PORRAS BUENO, Cristian Orlando; BERDUGO PEREIRA, Eliana Milena and SANTAMARIA ALZA, Yeison. Acute myeloid leukemya and relapsing polychondritis. Chance or causal relationship?. Rev Cuba Reumatol [online]. 2020, vol.22, n.2 Epub Aug 01, 2020. ISSN 1817-5996.
Relapsing polychondritis is a systemic, chronic and autoimmune disease characterized by the inflammation of cartilaginous tissues. This disease is associated in a few cases with malignant hematological diseases. We present a case of a patient with relapsing polychondritis and concomitantly with acute myeloid leukemia. A 26-year-old female patient, with cutaneous affection as initial manifestation categorized as erythema nodosum. Then she was diagnosed with acute myeloid leukemia. In the aplasia post-chemotherapy phase, the patient developed bilateral inflammation of the ear cartilage (auricular chondritis) and a vertiginous syndrome with satisfactory clinical evolution to immunosuppressive treatment with glucocorticoids.
Conclusion:
Relapsing polychondritis usually presents with cartilaginous involvement, such as bilateral atrial chondritis, as shown in the case. Early diagnosis and timely treatment are necessary to achieve a good clinical response. Subsequent studies are necessary to evaluate the association between relapsing polychondritis and hematological alterations such as acute myeloid leukemia and the use of chemotherapy.
Keywords : polychondritis; relapsing; leukemia myeloid acute; erythema nodosum ear cartilage.
